Objective to estimate the cost effectiveness of cilostazol pletal compared to naftidrofuryl and pentoxifylline trental in the treatment of intermittent claudication in the uk.
Info about Pletal.
Before taking cilostazoltell your doctor or pharmacist if you are allergic to itor if you have any other allergiesThis product may contain inactive ingredientswhich can cause allergic reactions or other problemsTalk to your pharmacist for more details.
The physician should reassess the patient after 3 months of treatment with a view to discontinuing cilostazol where an inadequate effect is observed or symptoms have not been improved.
In a single-dose clinical studyno inhibition of the metabolism of order pletal drug or an effect order pletal drug the coagulation parametersPTaPTTbleeding timewas observedHowevercaution is advised in patients receiving both cilostazol and any anticoagulant agentand frequent monitoring is required to reduce the possibility of bleeding.
Caution should be exercised when prescribing cilostazol for patients with atrial or ventricular ectopy and patients with atrial fibrillation or flutter.
Caution is needed when order pletal drug-administering cilostazol with any other agent which has the potential to reduce blood pressure due order pletal drug the possibility that there may be an additive hypotensive effect with a reflex tachycardia.
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Cilostazol is used to improve the symptoms of a certain blood flow problem in the legsintermittent claudicationCilostazol can decrease the muscle order pletal drug/cramps that occur during exercise/walkingClaudication pain is caused by order pletal drug little oxygen getting to the musclesCilostazol can increase blood flow and the amount of oxygen that gets to the muscles.
The suitability of treatment with cilostazol should be carefully considered alongside other treatment options such as revascularisation.
Blood glucose increasedblood uric acid increasedincrease in BUNblood urea increasedblood pressure increase.
In a single-dose clinical studyno inhibition of the metabolism of warfarin or an effect on the coagulation parametersPTaPTTbleeding timewas observedHowevercaution is advised in patients receiving both cilostazol and any anticoagulant agentand frequent monitoring Cloud mining 24 windows – Profitable is required to reduce the possibility of bleeding.
Concomitant administration of cilostazol and clopidogrel did not have any effect on platelet countprothrombin timePTor activated partial thromboplastin timeaPTTAll healthy subjects in the study had a prolongation of bleeding time on clopidogrel alone and concomitant administration with cilostazol order pletal drug not result in a significant additional effect on bleeding timeCaution is advised when co-administering cilostazol with any drug that inhibits platelet aggregationConsideration should be given to monitoring the bleeding time at intervalsCilostazol treatment is contraindicated in patients receiving two or more additional antiplatelet/anticoagulant order pletal drug section 4.3
Your symptoms may improve in 2-4 weeksbut it may take up to 12 weeks before you get the full benefit of this drug.
Cilostazol should be initiated by physicians experienced in the management of intermittent claudicationsee also section 4.4
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